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Summary

French nuclear tests irradiate an iguana into a giant monster that viciously attacks freighter ships in the Pacific Ocean. A team of experts, including Niko Tatopoulos, conclude that the oversized reptile is the culprit. Before long, the giant lizard is loose in Manhattan as the US military races to destroy the monster before it reproduces and it's spawn takes over the world.

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Cast

  • Matthew Broderick

    Matthew Broderick

    Dr. Niko Tatopoulos

  • Jean Reno

    Jean Reno

    Philippe Roaché

  • Maria Pitillo

    Maria Pitillo

    Audrey Timmonds

  • Hank Azaria

    Hank Azaria

    Victor 'Animal' Palotti

  • Kevin Dunn

    Kevin Dunn

    Colonel Hicks

  • Michael Lerner

    Michael Lerner

    Mayor Ebert

  • Harry Shearer

    Harry Shearer

    Charles Caiman

  • Arabella Field

    Arabella Field

    Lucy Palotti

  • Vicki Lewis

    Vicki Lewis

    Dr. Elsie Chapman

  • Doug Savant

    Doug Savant

    Sergeant O'Neal

  • Malcolm Danare

    Malcolm Danare

    Dr. Mendel Craven

  • Philippe Bergeron

    Philippe Bergeron

    Jean-Claude

  • Nicholas J. Giangiulio

    Nicholas J. Giangiulio

    Ed

  • Robert Lesser

    Robert Lesser

    Murray

  • Ralph Manza

    Ralph Manza

    Old Fisherman

  • Chris Ellis

    Chris Ellis

    General Anderson

  • Nancy Cartwright

    Nancy Cartwright

    Caiman's Secretary

  • Richard Gant

    Richard Gant

    Admiral Phelps

  • Steve Giannelli

    Steve Giannelli

    Jules

  • Bodhi Elfman

    Bodhi Elfman

    Freddie

  • Rich Grosso

    Rich Grosso

    Jimmy

  • Lloyd Kino

    Lloyd Kino

    Japanese Tanker Cook

  • Toshi Toda

    Toshi Toda

    Japanese Tanker Captain

  • Clyde Kusatsu

    Clyde Kusatsu

    Japanese Tanker Skipper

  • Masaya Kato

    Masaya Kato

    Japanese Tanker Crew Member

  • Glenn Morshower

    Glenn Morshower

    Kyle Terrington

  • Lola Pashalinski

    Lola Pashalinski

    Pharmacist

  • Derek Webster

    Derek Webster

    Utah Captain

  • Stuart Fratkin

    Stuart Fratkin

    Utah Ensign

  • David Pressman

    David Pressman

    Anchorage Captain

  • Ali Afshar

    Ali Afshar

    Anchorage Sailor

  • Kirk Geiger

    Kirk Geiger

    Apache Pilot

  • Pat Mastroianni

    Pat Mastroianni

    Apache Pilot

  • Eric Saiet

    Eric Saiet

    Apache Pilot

  • Burt Bulos

    Burt Bulos

    Apache Pilot

  • Robert Floyd

    Robert Floyd

    Apache Pilot

  • Seth Peterson

    Seth Peterson

    Apache Pilot

  • Jamison Yang

    Jamison Yang

    F-18 Pilot

  • Nathan Anderson

    Nathan Anderson

    F-18 Pilot

  • Greg Collins

    Greg Collins

    Soldier on the Bridge

  • James Black

    James Black

    Soldier

  • Thomas Giuseppe Giantonelli

    Thomas Giuseppe Giantonelli

    Soldier

  • Montae Russell

    Montae Russell

    Soldier on Plane

  • Daniel Pearce

    Daniel Pearce

    Radio Technician

  • Mark Fite

    Mark Fite

    Radio Operator

  • Craig 'Radioman' Castaldo

    Craig 'Radioman' Castaldo

    Radio Man

  • Eric Paskel

    Eric Paskel

    Rodgers

  • Lee Weaver

    Lee Weaver

    Homeless Guy

  • Leonard Termo

    Leonard Termo

    Homeless Guy

  • Al Sapienza

    Al Sapienza

    Taxi Cab Driver

  • Ed Wheeler

    Ed Wheeler

    New York Cop

  • Bill Hoag

    Bill Hoag

    New Jersey Cop

  • Benjamin Baird

    Benjamin Baird

    Reporters

  • Frank Welker

    Frank Welker

    Creature Vocals (voice)

  • Al Leong

    Al Leong

    Japanese Fishing Boat Crewman

  • Steven Ho

    Steven Ho

    Japanese Fishing Boat Crewman (uncredited)

  • George Cheung

    George Cheung

    Japanese Fishing Boat Crewman (uncredited)

  • John Koyama

    John Koyama

    Japanese Fishing Boat Crewman (uncredited)